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POSTORGASMIC ILLNESS SYNDROME: CAUSES, SYMPTOMS, AND TREATMENT OPTIONS RU EN ES

4 min read Sexual Health

Orgasms are the pinnacle of human sexual pleasure and release, but they can also come with some surprising side effects. One of these is that orgasms can cause temporary muscle spasms throughout the body. This phenomenon is known as post-orgasmic illness syndrome (POIS) or postcoital dysphoria. It's estimated to affect up to 1% of men worldwide, although it may be underdiagnosed. POIS symptoms typically begin within hours of an orgasm and last for days, though sometimes longer. They include a range of physical reactions including headaches, fatigue, joint pain, swelling, nausea, diarrhea, vomiting, and genital pain. While the exact cause of POIS is unknown, research suggests that inflammation may play a role. Men who experience POIS often report feeling depressed or anxious after sex, which can lead to avoidance behaviors and relationship difficulties. Treatment options vary depending on the severity of symptoms but may involve antihistamines, steroids, antidepressants, or other medications. However, more research is needed to fully understand this condition and develop effective treatments. In the meantime, men experiencing POIS should speak openly with their partners and healthcare providers about their needs and concerns.

What exactly is POIS?

Post-orgasmic illness syndrome (POIS), also known as postcoital dysphoria, is a rare condition that occurs in some men following ejaculation. Symptoms start within hours of sexual activity and can persist for several days or even weeks. They are characterized by a wide range of physical and emotional side effects, including:

Headache, fatigue, and joint pain

Swelling and redness of the face, eyes, or genitals

Nausea, diarrhea, vomiting, and abdominal cramps

Reduced libido and difficulty achieving erections

Anxiety, depression, and social isolation

The exact cause of POIS remains unclear, but it appears to be related to an immune response triggered by ejaculation. Some researchers believe that certain proteins released during orgasm cause an autoimmune reaction that leads to inflammation throughout the body. This hypothesis is supported by the fact that POIS symptoms often improve when patients take immunosuppressive drugs such as corticosteroids or antihistamines.

How common is POIS?

POIS is estimated to affect up to 1% of men worldwide, though this may be an underestimate due to its underdiagnosis. It's most commonly seen in young adults between the ages of 20 and 40. Men with POIS often report feeling anxious, embarrassed, and ashamed about their symptoms, leading them to avoid sex altogether.

Treatment options for POIS

There is currently no definitive treatment for POIS, although various medications have been used with some success. In addition to steroids and antihistamines, antidepressants like fluoxetine (Prozac) and sertraline (Zoloft) have shown promise in reducing symptoms. These drugs work by blocking the release of a chemical called serotonin, which plays a role in mood regulation and sexual function. Patients may also benefit from lifestyle changes such as regular exercise, stress management, and healthy eating habits.

What does POIS mean for relationships?

For men with POIS, sexual activity can become a source of anxiety and distress rather than pleasure. They may feel isolated and alone, even if they are in a committed relationship. Partners may not understand why their partner suddenly withdraws after sex or becomes irritable and moody. This can lead to tension and conflict within the relationship. However, open communication and empathy are key to addressing these issues. Both partners should work together to find ways to manage symptoms and maintain intimacy without putting undue pressure on either person. With patience and understanding, couples can overcome this challenge and build stronger bonds.

In conclusion, POIS is an uncommon but debilitating condition that affects men's physical and emotional well-being. While more research is needed to fully understand its causes and develop effective treatments, patients can take steps to reduce their symptoms and improve their quality of life. By speaking openly about their needs and seeking support from loved ones and medical professionals, individuals with POIS can find ways to navigate this challenging condition and live fulfilling lives.

Want to learn more about POIS and other conditions related to sexuality and intimacy? Check out our blog post "7 Surprising Sexual Conditions You May Not Know About" for insights into common and rare disorders that impact sexual function.